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Cannabis and Pain: Who Uses it and How it Works

Cannabis plant

Cannabis and Pain: Who Uses it and How it Works

Pain is a problem for most at one time or another, and to varying degrees. The Center for Disease Control and Prevention (CDC) states that, in 2019, 20.4% of adults had chronic pain. And 7.4% of adults had chronic pain that limited life or work activities. That is a lot of pain.

Every day, people stay home from work, miss school, go to the doctor, or even die because of the effects of pain.

Whether from a hard workout, a physically demanding lifestyle, an illness, a chronic condition, or general discomfort, pain can do more than just make you uncomfortable. For many people, cannabis for pain is steadily gaining popularity as a natural approach to relief.

76 Million Americans Suffer from Pain

We’re seeing just how severe the pain problem really is. Respondents to a 2018 National Health Interview Survey reported the most common pain locations were back pain and hip, knee, or foot pain. Findings indicated that more than 1 in 5 adults in the United States experience chronic pain.

According to the American Pain Foundation, more than a quarter of Americans (26%) aged 20 years and over — or, an estimated 76.5 million Americans — reported a problem with pain of any sort that persisted for more than 24 hours.

The CDC estimates the total U.S. economic burden of pain prescription opioid misuse is $78.5 billion a year. This includes the costs of health care, lost productivity, addiction treatment, and criminal justice involvement. Some of these prescriptions may be warranted, but with states like Massachusetts legalizing the use of both medical and recreational marijuana, consumers in pain now have options.

Do People Use Cannabis for Pain?

Cannabis has been a natural pain remedy for centuries, long before there was any scientific research to prove its effectiveness. The first recorded medicinal use was in China circa 2900 B.C., and again in India in 1000 B.C.

Cannabis eventually arrived in the west where its benefits are only now being seriously explored.

According to a 2021 Harris Poll on chronic pain, twice as many Americans are using CBD or marijuana for pain than opioid medication. Cannabis for pain is the second most-prevalent pharmacological pain solution following traditional over-the-counter pain medication.

But just because a lot of people use cannabis doesn’t mean it always works. A 2017 Journal of Health Affairs survey on the effectiveness of cannabis for pain found ​that 84.6% of respondents found symptomatic relief for “evidence-based conditions.” 62.2% of respondents reported using marijuana for chronic pain.

How Cannabis Works for Pain

We all have an endocannabinoid system (ECS). “Endo” means inside and “cannabinoids” are cannabis compounds. We have cannabinoids already inside of us that our body naturally produces. And we have receptors for the cannabinoids to interact with.

This system helps the body establish and maintain balance for optimal health and wellness. The components of the ECS are expressed throughout the pain processing pathways. Cannabinoids like THC may enhance the efficacy of this system.

Here’s a little more information about how cannabis works for pain.

Anti-Inflammatory Properties

​​Inflammation typically causes pain because the swelling and buildup of tissue start pressing against nerve endings. This pressure sends pain signals to the brain, causing discomfort.

Inflammation is a large component of most pain. Evidence indicates that cannabinoids may contribute to pain relief through anti-inflammatory properties. Other components of the cannabis plant such as terpenes and flavonoids may also contribute to the anti-inflammatory effects of cannabis.

Mood Boost and Less Pain

Anandamide is an endocannabinoid commonly referred to as the “bliss molecule” because of the way it makes you feel. It’s notably found in chocolate, which may be one of the reasons chocolate is such a comfort food when we’re feeling down.

Fatty Acid Amide Hydrolase (FAAH) is the enzyme that breaks down anandamide. Some cannabinoids inhibit the FAAH enzyme. As a result, the breakdown of anandamide occurs slowly. This increases the levels of anandamide in the body, allowing the body to relax and experience less pain.

Communication is Key

One quality that sets cannabinoid receptors apart from other receptors in the body is their ability to conduct retrograde neuron signaling. That sounds pretty technical but stay with us.

Typically, one neuron sends a signal to another with information, but no information is returned. Anandamide is a retrograde messenger, which means that it can invoke a two-way (retrograde) communication system. The increased communication allows cells to receive information and respond according to signals received in the brain to promote balance. This includes pain signals.

Back Pain

Using Cannabis for Pain

Everyone experiences pain differently. How you choose to manage your condition is a personal choice. If you plan to try marijuana for pain, first speak to your care provider about what’s best for you, especially if you’re taking medication for an existing condition.

Cannabis comes in many forms, and the best way to consume will be unique to your preferences and needs. Available products may include flower, vaporizers, edibles, tinctures, or topicals.

It’s important to understand that your personal metabolism will impact how fast cannabis activates in your body to help with pain. Dosage will also be a factor.

The experienced staff at Fine Fettle can help you determine the dosage, format, and timing that are most likely to give you the results you’re seeking. We look forward to helping you find the right cannabis product for meaningful pain relief. Order online for quick pickup at one of our dispensaries in Connecticut and Massachusetts.

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